DIAZOLIDINYL URIA

Diazolidinyl Urea is a broad-spectrum, formaldehyde-releasing preservative commonly used in personal care, cosmetic, and pharmaceutical products. It effectively controls bacteria, yeasts, and molds at low concentrations, extending the shelf life of water-based formulations. Diazolidinyl Urea is compatible with a wide pH range and works well in leave-on and rinse-off applications.

Overview

Diazolidinyl Urea (commonly known under trade names such as Germall® II) is a white, free-flowing, water-soluble powder used as an antimicrobial preservative in cosmetics and personal care products. It functions by slowly releasing formaldehyde, which disrupts microbial DNA and protein synthesis. Diazolidinyl Urea is effective at low concentrations and provides long-lasting protection against Gram-positive and Gram-negative bacteria, fungi, and yeasts. It is typically used in conjunction with other preservatives like parabens or IPBC for enhanced performance. Its broad compatibility and established safety profile make it ideal for a wide range of formulations.

Benefits

  • Broad-Spectrum Activity – Effective against bacteria, fungi, and yeasts

  • Stable in Aqueous Formulations – Performs consistently in water-based products

  • Wide pH Range Compatibility – Suitable for pH 3.0 to 9.0

  • Low Usage Requirement – Effective at concentrations of 0.2% to 0.6%

  • Highly Compatible – Works well with other preservatives and ingredients

  • Ease of Use – Water-soluble powder that integrates smoothly into formulations

Applications

  • Personal Care Products – Preserves lotions, creams, gels, shampoos, and conditioners

  • Cosmetics & Makeup – Used in foundations, mascaras, and makeup removers

  • Pharmaceutical & Topical Products – Ensures sterility in creams and ointments

  • Household Products – Protects liquid detergents, fabric softeners, and cleaners

  • Industrial Emulsions – Used in lubricants, surfactants, and polymer dispersions

  • Baby Care & Sensitive Skin Formulas – Applied in low concentrations under regulatory limits

Properties Table

PropertyDetails
Product NameDiazolidinyl Urea
Chemical NameN,N”-Methylenebis(N’-[1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea)
Chemical TypeFormaldehyde-releasing antimicrobial preservative
Active IngredientDiazolidinyl Urea (≥98%)
Physical FormFine white powder
AppearanceOdorless white crystalline powder
OdorOdorless or very faint odor
pH (1% Solution)~6.0 – 7.5
SolubilityFreely soluble in water
Density~0.6 – 0.8 g/cm³ (bulk powder)
Flash PointNot applicable (non-flammable)
Recommended Use Level0.2% – 0.6% depending on product type
pH Stability Range3.0 – 9.0
Shelf Life24 months in sealed packaging
Packaging Options1 kg, 5 kg, 25 kg HDPE drums or fiber cartons

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